The hidden condition behind fatigue, anxiety and gut issues: eds & hsd?
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Are you or someone you know hyper flexible or "double jointed"? That enhanced flexibility may be a sign of Ehlers-Danlos Syndrome (EDS) or Hypermobility Spectrum Disorder (HSD) — conditions that can be a hidden root cause behind chronic pain, fatigue, anxiety, digestive issues, POTS and more. In this episode, Elwin Robinson walks through the diagnostic criteria, the surprising symptoms, the potential causes, and most importantly what you can actually do about it — from the Beighton self-test to nutrition, hormones, medications to avoid, and the exercise strategies that genuinely help.
References:
- Generic Health Advice Is Making You Sick by Elwin Robinson (Amazon)
- The Nutrient Gap by Elwin Robinson (Amazon)
- The Detox / Toxin Paradox by Elwin Robinson: https://rejuvenateblueprint.com
- Advanced Health Genetics hypermobility report: https://advancedhealthgenetics.com
EDS Society – Diagnostic Criteria: https://www.ehlers-danlos.com/diagnosis/
EDS Society – HEDGE Study: https://www.ehlers-danlos.com/the-hedge-study/
EDS Society – Road to 2026 FAQs: https://www.ehlers-danlos.com/road-to-2026/faqs/
GeneReviews – Hypermobile EDS: https://www.ncbi.nlm.nih.gov/books/NBK1279/
Hakim 2017 – Chronic Fatigue in hEDS: https://pubmed.ncbi.nlm.nih.gov/28186393/
Hugon-Rodin 2016 – Gynecologic Symptoms in hEDS: https://link.springer.com/10.1186/s13023-016-0511-2
Smith 2014 – Hypermobility, Anxiety and Depression Meta-analysis: https://dbpia.nl.go.kr/rheumatology/article-abstract/53/1/114/1782101
Mallorquí-Bagué 2014 – Interoception and Anxiety: https://www.frontiersin.org/articles/10.3389/fpsyg.2014.01162/full
Eccles 2012 – Brain Structure and Hypermobility: https://pmc.ncbi.nlm.nih.gov/articles/PMC3365276
Csecs 2022 – Hypermobility in Neurodivergent Adults: https://pubmed.ncbi.nlm.nih.gov/35185636/
Eccles 2024 – Hypermobility and Long COVID: https://doaj.org/article/0cce4b0244144195892b622c74eb4bb8
Maxwell 2025 – POTS and Hypermobility: https://pubmed.ncbi.nlm.nih.gov/40352770/
Topan 2024 – Diet and Nutrition in hEDS/HSD: https://discovery.ucl.ac.uk/id/eprint/10182422/
Practical Gastroenterology 2024 – Nutrition in hEDS: https://practicalgastro.com/2024/06/17/nutritional-considerations-for-hypermobile-ehlers-danlos-syndrome/
CIDRAP – FDA Fluoroquinolone Warning: https://www.cidrap.umn.edu/antimicrobial-stewardship/fda-fluoroquinolones-may-cause-aortic-rupture-some
HMSA – HRT and Hypermobility: https://www.hypermobility.org/post/hrt-and-hypermobility
Rombaut – Physiotherapy in EDS and HSD: https://www.ehlers-danlos.com/wp-content/uploads/2022/10/PDF_pain_management_lies_rombaut.pdf
Fu & Levine – Exercise and POTS: https://pmc.ncbi.nlm.nih.gov/articles/PMC6289756/
Timestamps:
00:00 Is Being Flexible a Health Warning?
00:53 Common Symptoms Linked to Hypermobility
01:22 What Are EDS and HSD?
04:14 How Common Is Hypermobility?
06:46 Chronic Pain and EDS Explained
08:51 Why Hypermobility Causes Fatigue
10:18 Dysautonomia and POTS Explained
13:20 The Anxiety and Panic Connection
16:39 Hypermobility and Neurodivergence Link
18:21 Digestive Problems and Gastroparesis
20:48 Bruising, Bleeding, and Anesthetic Resistance
23:48 Bladder, Pelvic, and Period Problems
24:46 The Beighton Score Self-Test
31:59 Official Diagnostic Criteria Explained
38:12 What Actually Causes EDS?
40:57 Collagen Nutrients and Vitamin C
44:25 Hormones, Progesterone, and Testosterone
46:12 Why Yoga May Not Help You
49:08 Nutrition Advice and Why Fasting Hurts
52:37 Antibiotics and Medications to Avoid
1:00:38 Exercise Rehabilitation: The Three Joint Systems
1:06:00 Resistance Training Golden Rules
1:14:20 Best Exercises: Swimming and Pilates
1:15:59 Postures, Footwear, and Finding a Therapist
The Rejuvenate podcast is dedicated to looking at the real root causes of premature aging, and what we can do to 'turn back the clock' and feel younger and healthier again.
Disclaimer: This YouTube channel does not contain medical advice. I am NOT a doctor. The contents of this YouTube channel, such as videos, text, graphics, images and other material are intended for entertainment, informational and educational purposes only and not for the purpose of rendering medical advice. The contents of this YouTube channel are not intended to substitute for professional medical advice, diagnosis or treatment. Consult your physician for
Get the Book 90% OFF: https://rejuvenateblueprint.com
Discover Your Hormonal Archetype: https://hormetics.health/ and Optimize your Body Composition
Unlock your Genetic Blueprint and get Personalized Health Advice: https://advancedhealthgenetics.com/ Use code *“REJUVENATE”* to get *20% OFF* your first order
Learn about Elwin Robinson and find out about working with him 1 on 1 at his website: https://elwinrobinson.com
And check out his socials at: https://linktr.ee/elwinrobinson